catRAPID approach

catRAPID approach


by Gian

In the catRAPID approach, proteins and RNAs are associated with wave-packets that contain information on their binding ability.

The wave-packets are built using phenomenological potentials for secondary structure, hydrogen bonding and van der Waals propensities.

The interference between protein and RNA waves determines the binding probability of molecules (i.e., the catRAPID score). In analogy with the Standard Model of Particle Physics, proteins and RNAs can be regarded as particles carrying a signal. In this view, waves are associated with a "riboproteon" signal (analogous to the force carrier "boson").